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Zoe Nordquist

I am Zoe, artistic creator of the digital avatars of this site! Read more



Molecular dynamics simulations

Using Newton’s laws to simulate molecular motion, like these wiggling waters:

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Physics-based modeling of Hsp70-substrate binding

Molecular chaperones like DnaK help fold misfolded proteins,
but how do they distinguish well-folded, misfolded, and disordered regions?

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Protein-like nanopore dewetting

Why do some protein ion channels like the BK channel, which are quite large ~1.2 nm diameter, have vapor rather than physical barriers?

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BK Channel Hydrophobic Gating

Hydrophobic dewetting forms a vapor barrier and closes BK Channel; what role do specific mutations play in (de-)stabilizing this delicate liquid-vapor interplay?

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BK Gating Voltage Predictor

Given abundant mutational data, I’m leveraging molecular and statistical modeling to predict gating voltage of the BK channel.

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Guest lecture: Molecular Mechanics

I gave a lecture on molecular mechanics in Jianhan’s graduate-level statistical mechanics course. Read more

Undergraduate Research Mentoring

I have mentored a few undergraduate students at UMass Amherst (2019-2021). I hope to continue this in my own teaching career, through small projects, independent studies, and research projects integrated into courses.
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Scientific Storytelling

Effective scientific storytelling is similar to telling a fairy-tale.

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Natural Sciences First-Year Seminar

The goal of the FYS is to welcome first-year CNS students and prepare them for college and for a major in the sciences.
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