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Zoe Nordquist

I am Zoe. Check out my art and music! Read more



Hydrophobic Dewetting in protein ion channels and model nanopores

Hydrophobic dewetting forms a vapor barrier and closes BK Channel; how do mutations or drug-like molecules (de-)stabilize this delicate liquid-vapor interplay?

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Physics-based modeling of Hsp70-substrate binding

Molecular chaperones like DnaK help fold misfolded proteins,
but how do they distinguish well-folded, misfolded, and disordered regions?

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BK Gating Voltage Predictor

Given abundant mutational data, I’m leveraging molecular and statistical modeling to predict gating voltage of the BK channel.

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Molecular dynamics simulations

Using Newton’s laws to simulate molecular motion, like these wiggling waters:

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Computer-aided drug discovery

Using simulations of proteins and small molecules to identify new drug candidates

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Undergraduate Research Mentoring

I have mentored a few undergraduate students at UMass Amherst (2019-2021). I hope to continue this in my own teaching career, through small projects, independent studies, and research projects integrated into courses.
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Scientific Storytelling

Effective scientific storytelling is similar to telling a fairy-tale.

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Natural Sciences First-Year Seminar

The goal of the FYS is to welcome first-year CNS students and prepare them for college and for a major in the sciences. Read more

Guest lectures

  1. Molecular mechanics and additive protein force fields; UMass Chem 586 Statistical Mechanics
    • Feb 2020, Instructor: Dr. Jianhan Chen
  2. (Guest moderator) Student-led discussion on AlphaFold2 Nature paper; Amherst College Biophysics Seminar
    • Mar 2023, Instructor: Dr. Ashley Carter
  3. Drug design and CADD in Cancer Biology; UMB Grad. Program in Life Science 665 Cancer Biology: From Basic Research to the Clinic
    • Sep 2023, Instructor: Dr. Rena Lapidus.
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