Posts by Collection

Lincoln Addresses (excerpts)

we here highly resolve these dead shall not have died in vain Read more

Piano

I’m learning to play!

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Podcasts/YouTube

I listen to some podcasts and YouTube channels Read more

Swimming

I really enjoy swimming!

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Tennyson (Ulysses, excerpt)

that which we are, we are Read more

Erik Nordquist

This website, eriknordquist.com, is my website. Read more

Zoe Nordquist

I am Zoe. Check out my art and music! Read more

Computational design of cancer drugs with SILCS

PROTACs are powerful ways to expand the druggable proteome, critical in cancer and other challenging diseases, but their design is often slow and expensive. Hence, CADD is useful!

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Hydrophobic Dewetting in protein ion channels and model nanopores

Hydrophobic dewetting forms a vapor barrier and closes BK Channel; how do mutations or drug-like molecules (de-)stabilize this delicate liquid-vapor interplay?

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Biophysics and Machine Learning

It is often useful to leverage computational biophysical data and machine learning to fill gaps in experiments. I’ve used this approach with the chaperone Hsp70, BK channel, and to predict druggable sites.

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Molecular dynamics simulations

Using Newton’s laws to simulate molecular motion, like these wiggling waters:

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Computer-aided drug discovery

Using simulations of proteins and small molecules to identify new drug candidates

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Undergraduate Research Mentoring

Training Courses

I have taken several courses associated with CIRTL on the online learning platform edX, including:

• Introduction to Evidence-based Undergraduate STEM Teaching
• The Inclusive STEM Teaching Project

Scientific Storytelling

Effective scientific storytelling is similar to telling a fairy-tale.

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Natural Sciences First-Year Seminar

The goal of the FYS is to welcome first-year CNS students and prepare them for college and for a major in the sciences. Read more

Guest lectures

1. Molecular mechanics and additive protein force fields; UMass Chem 586 Statistical Mechanics
   • Feb 2020, Instructor: Dr. Jianhan Chen
2. (Guest moderator) Student-led discussion on AlphaFold2 Nature paper; Amherst College Biophysics Seminar
   • Mar 2023, Instructor: Dr. Ashley Carter
3. Drug design and CADD in Cancer Biology; UMB Grad. Program in Life Science 665 Cancer Biology: From Basic Research to the Clinic
   • Sep 2023, Instructor: Dr. Rena Lapidus.